Drug Information

Drug General Information
Drug ID
D0F470
Drug Name
FP-025
Indication Asthma [ICD9: 493; ICD10:J45] Phase 1 [1725890]
Target and Pathway
Target(s) MMP-12 Target Info Inhibitor [1725885]
NetPath Pathway IL1 Signaling Pathway
IL5 Signaling Pathway
Pathway Interaction Database Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
Reactome Collagen degradation
Degradation of the extracellular matrix
WikiPathways TGF beta Signaling Pathway
Degradation of collagen
Matrix Metalloproteinases
References
Ref 1725890ClinicalTrials.gov (NCT02238834) Phase 1 Safety, Tolerability and Pharmacokinetics (PK) Study of FP-025 in Healthy Volunteers
Ref 1725885Potential clinical implications of recent matrix metalloproteinase inhibitor design strategies.