Drug Information

Drug General Information
Drug ID
D0H7KP
Former ID
DNC014547
Drug Name
(3-Amino-1-hydroxy-propyl)-methyl-phosphinic acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [533678]
Formula
C4H12NO3P
Canonical SMILES
CP(=O)(C(CCN)O)O
InChI
1S/C4H12NO3P/c1-9(7,8)4(6)2-3-5/h4,6H,2-3,5H2,1H3,(H,7,8)
InChIKey
VHBRTSZUHRQZQW-UHFFFAOYSA-N
PubChem Compound ID
10351876
Target and Pathway
Target(s) Gamma-aminobutyric acid B receptor Target Info Inhibitor [533678]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
GABAergic synapse
Estrogen signaling pathway
Morphine addiction
Reactome Activation of G protein gated Potassium channels
G alpha (i) signalling events
Class C/3 (Metabotropic glutamate/pheromone receptors)
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
WikiPathways GPCRs, Class C Metabotropic glutamate, pheromone
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Potassium Channels
GPCR ligand binding
GPCR downstream signaling
References
Ref 533678J Med Chem. 1995 Aug 18;38(17):3297-312.Phosphinic acid analogues of GABA. 1. New potent and selective GABAB agonists.
Ref 533678J Med Chem. 1995 Aug 18;38(17):3297-312.Phosphinic acid analogues of GABA. 1. New potent and selective GABAB agonists.