Drug Information

Drug General Information
Drug ID
D0I4YK
Former ID
DNC000932
Drug Name
Methanandamide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539628]
Formula
C23H39NO2
InChI
InChI=1S/C23H39NO2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-23(26)24-22(2)21-25/h7-8,10-11,13-14,16-17,22,25H,3-6,9,12,15,18-21H2,1-2H3,(H,24,26)/b8-7-,11-10-,14-13-,17-16-/t22-/m1/s1
InChIKey
SQKRUBZPTNJQEM-FQPARAGTSA-N
CAS Number
CAS 157182-49-5
PubChem Compound ID
6321351
PubChem Substance ID
7850560, 7979921, 11598741, 14803494, 24896698, 26754852, 26754853, 26754854, 42971261, 47290862, 47588722, 47885128, 50110804, 53801074, 57309611, 57365602, 72404826, 76249586, 85788014, 91721439, 92309701, 99300615, 99302133, 103348814, 103951081, 104046468, 114478911, 134340217, 137249377, 139263848, 142712356, 162226840, 179205485, 226674439, 241182147, 241375230, 249966148, 252156089, 252455425, 252457535, 252463350
Target and Pathway
Target(s) Cannabinoid receptor 1 Target Info Antagonist [537268]
KEGG Pathway Rap1 signaling pathway
Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
PANTHER Pathway Endogenous cannabinoid signaling
Pathway Interaction Database N-cadherin signaling events
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
BDNF signaling pathway
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 539628(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2506).
Ref 537268Methanandamide attenuates cocaine-induced hyperthermia in rats by a cannabinoid CB(1)-dopamine D(2) receptor mechanism. Brain Res. 2009 Jan 17.