Drug General Information
Drug ID
D0M4ZK
Former ID
DNC007172
Drug Name
10-methoxy-ginkgolide C
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528727]
Formula
C21H26O11
Canonical SMILES
CC1C(=O)OC2C1(C34C5(C2O)C(C(C(C56C(C(=O)OC6O3)OC)C(C)(C<br />)C)O)C(=O)O4)O
InChI
1S/C21H26O11/c1-6-13(24)29-11-10(23)19-7-8(22)9(17(2,3)4)18(19)12(28-5)15(26)30-16(18)32-21(19,20(6,11)27)31-14(7)25/h6-12,16,22-23,27H,1-5H3/t6-,7+,8+,9+,10+,11+,12+,16+,18+,19+,20-,21+/m1/s1
InChIKey
RYOIKJMKJWXJLR-XWGAEZTCSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Glycine receptor Target Info Inhibitor [528727]
Glycine receptor alpha-1 chain Target Info Inhibitor [528727]
KEGG Pathway Neuroactive ligand-receptor interactionhsa04080:Neuroactive ligand-receptor interaction
Reactome Ligand-gated ion channel transportR-HSA-975298:Ligand-gated ion channel transport
WikiPathways Iron uptake and transport
References
Ref 528727J Med Chem. 2007 Apr 5;50(7):1610-7. Epub 2007 Mar 13.Probing the pharmacophore of ginkgolides as glycine receptor antagonists.
Ref 528727J Med Chem. 2007 Apr 5;50(7):1610-7. Epub 2007 Mar 13.Probing the pharmacophore of ginkgolides as glycine receptor antagonists.