Drug Information

Drug General Information
Drug ID
D0N1PW
Former ID
DNC014612
Drug Name
4-Indol-1-ylmethyl-benzamidine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [533527]
Formula
C16H15N3
Canonical SMILES
C1=CC=C2C(=C1)C=CN2CC3=CC=C(C=C3)C(=N)N
InChI
1S/C16H15N3/c17-16(18)14-7-5-12(6-8-14)11-19-10-9-13-3-1-2-4-15(13)19/h1-10H,11H2,(H3,17,18)
InChIKey
VKEKMIKRPJWXHO-UHFFFAOYSA-N
PubChem Compound ID
134348
Target and Pathway
Target(s) Trypsin Target Info Inhibitor [533527]
KEGG Pathway Neuroactive ligand-receptor interaction
Pancreatic secretion
Protein digestion and absorption
Influenza A
Reactome Activation of Matrix Metalloproteinases
Cobalamin (Cbl, vitamin B12) transport and metabolism
WikiPathways Activation of Matrix Metalloproteinases
References
Ref 533527J Med Chem. 1983 Feb;26(2):294-8.Aromatic amidines: comparison of their ability to block respiratory syncytial virus induced cell fusion and to inhibit plasmin, urokinase, thrombin, and trypsin.
Ref 533527J Med Chem. 1983 Feb;26(2):294-8.Aromatic amidines: comparison of their ability to block respiratory syncytial virus induced cell fusion and to inhibit plasmin, urokinase, thrombin, and trypsin.