Drug Information

Drug General Information
Drug ID
D0N2QX
Former ID
DNC003535
Drug Name
3-(trifluoromethyl)benzaldehyde thiosemicarbazone
Drug Type
Small molecular drug
Indication Discovery agent Investigative [526354]
Formula
C9H8F3N3S
Canonical SMILES
C1=CC(=CC(=C1)C(F)(F)F)C=NNC(=S)N
InChI
1S/C9H8F3N3S/c10-9(11,12)7-3-1-2-6(4-7)5-14-15-8(13)16/h1-5H,(H3,13,15,16)/b14-5+
InChIKey
GDIMOASDCOFPTD-LHHJGKSTSA-N
PubChem Compound ID
9580972
Target and Pathway
Target(s) Cruzipain Target Info Inhibitor [526354]
References
Ref 526354J Med Chem. 2002 Jun 20;45(13):2695-707.Synthesis and structure-activity relationship study of potent trypanocidal thio semicarbazone inhibitors of the trypanosomal cysteine protease cruzain.
Ref 526354J Med Chem. 2002 Jun 20;45(13):2695-707.Synthesis and structure-activity relationship study of potent trypanocidal thio semicarbazone inhibitors of the trypanosomal cysteine protease cruzain.