Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0N5HN
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| Former ID |
DCL000160
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| Drug Name |
M-100240
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| Synonyms |
Mdl 100240; M100,240; MDL-100240; Mdl 100,142; Mdl 100,240; (4S,7S,12bR)-7-[[(2S)-2-acetylsulfanyl-3-phenylpropanoyl]amino]-6-oxo-2,3,4,7,8,12b-hexahydro-1H-pyrido[2,1-a][2]benzazepine-4-carboxylic acid
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| Drug Type |
Small molecular drug
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| Indication | Hypotension [ICD9: 458, 796.3; ICD10:I95] | Discontinued in Phase 2 | [545322] | ||
| Company |
Aventis Pharma
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| Formula |
C26H28N2O5S
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| Canonical SMILES |
CC(=O)SC(CC1=CC=CC=C1)C(=O)NC2CC3=CC=CC=C3C4CCCC(N4C2=O<br />)C(=O)O
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| InChI |
1S/C26H28N2O5S/c1-16(29)34-23(14-17-8-3-2-4-9-17)24(30)27-20-15-18-10-5-6-11-19(18)21-12-7-13-22(26(32)33)28(21)25(20)31/h2-6,8-11,20-23H,7,12-15H2,1H3,(H,27,30)(H,32,33)/t20-,21+,22-,23-/m0/s1
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| InChIKey |
AIEZUMPHACQOGT-BJESRGMDSA-N
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| CAS Number |
CAS 142695-08-7
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Neutral endopeptidase | Target Info | Modulator | ||
| Angiotensin-converting enzyme | Target Info | Modulator | |||
| NetPath Pathway | EGFR1 Signaling Pathway | ||||
| TGF_beta_Receptor Signaling Pathway | |||||
| PathWhiz Pathway | Angiotensin Metabolism | ||||
| References | |||||