Drug Information

Drug General Information
Drug ID
D0N6MR
Former ID
DNC004194
Drug Name
1,3-Dihydro-imidazo[4,5-b]quinolin-2-one
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528087]
Formula
C10H7N3O
Canonical SMILES
C1=CC=C2C(=C1)C=C3C(=N2)NC(=O)N3
InChI
1S/C10H7N3O/c14-10-12-8-5-6-3-1-2-4-7(6)11-9(8)13-10/h1-5H,(H2,11,12,13,14)
InChIKey
BINWKEIURMBREF-UHFFFAOYSA-N
PubChem Compound ID
10867033
Target and Pathway
Target(s) CGMP-inhibited 3',5'-cyclic phosphodiesterase A Target Info Inhibitor [528087]
KEGG Pathway Purine metabolism
cGMP-PKG signaling pathway
cAMP signaling pathway
Morphine addiction
Reactome cGMP effects
G alpha (s) signalling events
WikiPathways miR-targeted genes in muscle cell - TarBase
miR-targeted genes in lymphocytes - TarBase
References
Ref 528087J Med Chem. 1991 Sep;34(9):2906-16.1,3-Dihydro-2H-imidazo[4,5-b]quinolin-2-ones--inhibitors of blood platelet cAMP phosphodiesterase and induced aggregation.
Ref 528087J Med Chem. 1991 Sep;34(9):2906-16.1,3-Dihydro-2H-imidazo[4,5-b]quinolin-2-ones--inhibitors of blood platelet cAMP phosphodiesterase and induced aggregation.