Drug General Information
Drug ID
D0N7JZ
Former ID
DIB012408
Drug Name
SAND-26
Synonyms
Begedina; CD26-targeting antibody (autoimmunity), ADIENNE
Drug Type
Antibody
Indication Autoimmune diabetes [ICD10:E08-E13] Phase 3 [525143], [543248]
Company
ADIENNE Pharma & Biotech
Target and Pathway
Target(s) Dipeptidyl peptidase IV Target Info [551687]
KEGG Pathway Protein digestion and absorption
NetPath Pathway IL2 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
References
Ref 525143ClinicalTrials.gov (NCT02411084) Study of BEGEDINA vs "Conventional Treatment" for Treating Steroid-Resistant Acute GvHD. U.S. National Institutes of Health.
Ref 543248(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8691).
Ref 551687Clinical pipeline report, company report or official report of Siesonline.