Drug Information

Drug General Information
Drug ID
D0O5ZG
Former ID
DNC004018
Drug Name
1-Methoxy-6-phenyl-6H-benzo[c]chromene
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527034]
Formula
C20H16O2
Canonical SMILES
COC1=CC=CC2=C1C3=CC=CC=C3C(O2)C4=CC=CC=C4
InChI
1S/C20H16O2/c1-21-17-12-7-13-18-19(17)15-10-5-6-11-16(15)20(22-18)14-8-3-2-4-9-14/h2-13,20H,1H3
InChIKey
SZYXTCHBPGBQPM-UHFFFAOYSA-N
PubChem Compound ID
44305900
Target and Pathway
Target(s) mRNA of glucocorticoid receptor Target Info Inhibitor [527034]
KEGG Pathway Neuroactive ligand-receptor interaction
NetPath Pathway IL2 Signaling Pathway
TCR Signaling Pathway
Pathway Interaction Database Regulation of nuclear SMAD2/3 signaling
Signaling events mediated by HDAC Class II
FOXA2 and FOXA3 transcription factor networks
Glucocorticoid receptor regulatory network
Regulation of Androgen receptor activity
AP-1 transcription factor network
Reactome BMAL1:CLOCK,NPAS2 activates circadian gene expression
WikiPathways Serotonin Receptor 4/6/7 and NR3C Signaling
SIDS Susceptibility Pathways
Endoderm Differentiation
Hair Follicle Development: Cytodifferentiation (Part 3 of 3)
Adipogenesis
Circadian Clock
Nuclear Receptors
References
Ref 527034Bioorg Med Chem Lett. 2004 May 3;14(9):2079-82.Synthesis and biological evaluation of novel, selective, nonsteroidal glucocorticoid receptor antagonists.
Ref 527034Bioorg Med Chem Lett. 2004 May 3;14(9):2079-82.Synthesis and biological evaluation of novel, selective, nonsteroidal glucocorticoid receptor antagonists.