Drug Information

Drug General Information
Drug ID
D0P7JE
Former ID
DNC002604
Drug Name
S,S-(2-Hydroxyethyl)Thiocysteine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551393]
Formula
C5H10NO3S2-
Canonical SMILES
C(CSSCC(C(=O)[O-])N)O
InChI
1S/C5H11NO3S2/c6-4(5(8)9)3-11-10-2-1-7/h4,7H,1-3,6H2,(H,8,9)/p-1/t4-/m0/s1
InChIKey
YPUBRSXDQSFQBA-BYPYZUCNSA-M
PubChem Compound ID
6857709
PubChem Substance ID
11534238, 43493766, 78940991, 114696824
Target and Pathway
Target(s) Thymidylate synthase Target Info Inhibitor [551393]
DTDP-4-dehydrorhamnose 3,5-epimerase rmlC Target Info Inhibitor [551393]
CAMP-specific 3',5'-cyclic phosphodiesterase 4B Target Info Inhibitor [551393]
Maspin Target Info Inhibitor [551393]
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1 Target Info Inhibitor [551393]
Delta-aminolevulinic acid dehydratase Target Info Inhibitor [551393]
BioCyc Pathway Pyrimidine deoxyribonucleotides biosynthesis from CTP
Pyrimidine deoxyribonucleotides de novo biosynthesis
Superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis
Superpathway of pyrimidine deoxyribonucleoside salvage
DTMP de novo biosynthesis (mitochondrial)
Pyrimidine deoxyribonucleosides salvagePWY-5920:Heme biosynthesis
Tetrapyrrole biosynthesis
KEGG Pathway Pyrimidine metabolism
One carbon pool by folate
Metabolic pathwayshsa00230:Purine metabolism
cAMP signaling pathway
Morphine addictionhsa04115:p53 signaling pathway
MicroRNAs in cancerhsa00860:Porphyrin and chlorophyll metabolism
Metabolic pathways
NetPath Pathway IL5 Signaling Pathway
IL2 Signaling Pathway
PANTHER Pathway De novo pyrimidine deoxyribonucleotide biosynthesis
Formyltetrahydroformate biosynthesisP00059:p53 pathwayP02746:Heme biosynthesis
Pathway Interaction Database E2F transcription factor networkp53downstreampathway:Direct p53 effectors
ATF-2 transcription factor network
Validated transcriptional targets of TAp63 isoforms
PathWhiz Pathway Pyrimidine MetabolismPW000158:Porphyrin Metabolism
Reactome E2F mediated regulation of DNA replication
Pyrimidine biosynthesis
G1/S-Specific TranscriptionR-HSA-180024:DARPP-32 events
G alpha (s) signalling events
WikiPathways Trans-sulfuration and one carbon metabolism
Retinoblastoma (RB) in Cancer
One Carbon Metabolism
Integrated Pancreatic Cancer Pathway
miR-targeted genes in muscle cell - TarBase
miR-targeted genes in lymphocytes - TarBase
miR-targeted genes in leukocytes - TarBase
miR-targeted genes in epithelium - TarBase
Metabolism of nucleotides
Fluoropyrimidine ActivityWP35:G Protein Signaling Pathways
Myometrial Relaxation and Contraction Pathways
Nuclear Receptors Meta-Pathway
Opioid SignallingWP561:Heme Biosynthesis
Metabolism of porphyrins
References
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.