Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0Q5ZJ
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| Former ID |
DNC000182
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| Drug Name |
Alpha-estradiol
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [534842] | ||
| Structure |
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Download |
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| Formula |
C18H24O2
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| Canonical SMILES |
CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)O
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| InChI |
1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17-,18+/m1/s1
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| InChIKey |
VOXZDWNPVJITMN-SFFUCWETSA-N
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| CAS Number |
CAS 57-91-0
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| PubChem Compound ID | |||||
| PubChem Substance ID |
5544, 82900, 8139857, 8143675, 8192210, 11364694, 11367256, 11369818, 11372859, 11375418, 11377981, 12146107, 14897274, 15221951, 22391544, 24702251, 24894682, 26755326, 26755327, 43125123, 46488040, 47217073, 48421883, 49688698, 50087220, 50473417, 51091460, 56310604, 57316935, 57392211, 91704112, 92298710, 92721154, 93165615, 103097915, 104234168, 104342496, 124892354, 124892355, 126523270, 126619403, 129506091, 134971198, 135727368, 137003335, 139780840, 144208460, 144213948, 162228627, 163138824
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| ChEBI ID |
ChEBI:17160
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| Target and Pathway | |||||
| Target(s) | Androgen receptor | Target Info | Antagonist | [534842] | |
| Pathway Interaction Database | Regulation of nuclear SMAD2/3 signaling | ||||
| Coregulation of Androgen receptor activity | |||||
| Regulation of Androgen receptor activity | |||||
| Nongenotropic Androgen signaling | |||||
| Regulation of nuclear beta catenin signaling and target gene transcription | |||||
| FOXA1 transcription factor network | |||||
| Notch-mediated HES/HEY network | |||||
| References | |||||