Drug Information

Drug General Information
Drug ID
D0QE3V
Former ID
DNC005785
Drug Name
L-888607
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539207]
Formula
C19H15ClFNO2S
InChI
InChI=1S/C19H15ClFNO2S/c20-12-1-4-14(5-2-12)25-19-15-6-3-13(21)10-16(15)22-8-7-11(18(19)22)9-17(23)24/h1-6,10-11H,7-9H2,(H,23,24)/t11-/m0/s1
InChIKey
GSBAVONRPNJJOH-NSHDSACASA-N
PubChem Compound ID
44403763
PubChem Substance ID
90048934, 103469505, 104060179, 134342990, 135650504, 198964162, 223370138, 223565987
Target and Pathway
Target(s) Putative G-protein coupled receptor 44 Target Info Inhibitor [527768]
Reactome Prostanoid ligand receptors
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 539207(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1907).
Ref 527768J Med Chem. 2005 Oct 6;48(20):6174-7.Indole-3-acetic acid antagonists of the prostaglandin D2 receptor CRTH2.