Drug Information

Drug General Information
Drug ID
D0R1KE
Former ID
DNC006920
Drug Name
2-(4-bromo-2-(hydroxymethyl)phenoxy)acetic acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528566]
Formula
C9H9BrO4
Canonical SMILES
C1=CC(=C(C=C1Br)CO)OCC(=O)O
InChI
1S/C9H9BrO4/c10-7-1-2-8(6(3-7)4-11)14-5-9(12)13/h1-3,11H,4-5H2,(H,12,13)
InChIKey
QMNTWAAGYOSTJK-UHFFFAOYSA-N
PubChem Compound ID
894151
Target and Pathway
Target(s) Putative G-protein coupled receptor 44 Target Info Inhibitor [528566]
Reactome Prostanoid ligand receptors
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 528566J Med Chem. 2006 Nov 16;49(23):6638-41.Novel selective orally active CRTH2 antagonists for allergic inflammation developed from in silico derived hits.
Ref 528566J Med Chem. 2006 Nov 16;49(23):6638-41.Novel selective orally active CRTH2 antagonists for allergic inflammation developed from in silico derived hits.