Drug General Information
Drug ID
D0R8JK
Former ID
DNC009660
Drug Name
N-phenyl-6-(sulfamoylamino)hexanamide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529866]
Formula
C12H19N3O3S
Canonical SMILES
C1=CC=C(C=C1)NC(=O)CCCCCNS(=O)(=O)N
InChI
1S/C12H19N3O3S/c13-19(17,18)14-10-6-2-5-9-12(16)15-11-7-3-1-4-8-11/h1,3-4,7-8,14H,2,5-6,9-10H2,(H,15,16)(H2,13,17,18)
InChIKey
GJBBLVDVDAQQMI-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) Histone deacetylase 6 Target Info Inhibitor [529866]
KEGG Pathway Alcoholism
Viral carcinogenesis
Pathway Interaction Database Signaling events mediated by HDAC Class II
Signaling events mediated by HDAC Class I
Reactome NOTCH1 Intracellular Domain Regulates Transcription
Constitutive Signaling by NOTCH1 PEST Domain Mutants
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
Assembly of the primary cilium
WikiPathways Ectoderm Differentiation
Neural Crest Differentiation
Cell Cycle
References
Ref 529866Bioorg Med Chem Lett. 2009 Jan 15;19(2):336-40. Epub 2008 Nov 27.Sulfamides as novel histone deacetylase inhibitors.
Ref 529866Bioorg Med Chem Lett. 2009 Jan 15;19(2):336-40. Epub 2008 Nov 27.Sulfamides as novel histone deacetylase inhibitors.