Drug General Information
Drug ID
D0U0AY
Former ID
DIB009221
Drug Name
AV-101
Synonyms
Anti-epileptic, VistaGen; L-4-chlorokynurenine; NMDA receptor antagonists, University of Maryland/VistaGen; 4-Cl-kynurenine, NIH/VistaGen; 7-Chlorokynurenic acid; 7-Cl-KYN; 7-Cl-KYNA, NIH
Indication Neuropathic pain [ICD9: 356.0, 356.8; ICD10:G64, G90.0] Phase 2 [525245]
Company
Vistagen therapeutics
Canonical SMILES
c1(C(=O)C[C@@H](C(=O)O)N)c(cc(cc1)Cl)N
Target and Pathway
Target(s) NMDA receptor Target Info Antagonist [551769]
References
Ref 525245ClinicalTrials.gov (NCT02484456) Antidepressant Effects of the Glycine Receptor Antagonist AV-101 (4-chlorokynurenine) in Major Depressive Disorder.
Ref 551769Clinical pipeline report, company report or official report of VistaGen Therapeutics, Inc.