Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0U7QE
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| Former ID |
DNC010603
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| Drug Name |
[Tdf1]AngII
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| Indication | Discovery agent | Investigative | [530710] | ||
| Formula |
C57H74F3N15O10
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| Canonical SMILES |
CCC(C)C(C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)NC(CC3=CC=C<br />C=C3)C(=O)O)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(C(C)C)NC(=O<br />)C(CCCN=C(N)N)NC(=O)C(CC5=CC=C(C=C5)C6(N=N6)C(F)(F)F)N
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| InChI |
1S/C57H74F3N15O10/c1-5-32(4)46(52(82)69-42(28-37-29-64-30-66-37)53(83)75-24-10-14-44(75)50(80)70-43(54(84)85)27-33-11-7-6-8-12-33)72-49(79)41(26-35-17-21-38(76)22-18-35)68-51(81)45(31(2)3)71-48(78)40(13-9-23-65-55(62)63)67-47(77)39(61)25-34-15-19-36(20-16-34)56(73-74-56)57(58,59)60/h6-8,11-12,15-22,29-32,39-46,76H,5,9-10,13-14,23-28,61H2,1-4H3,(H,64,66)(H,67,77)(H,68,81)(H,69,82)(H,70,80)(H,71,78)(H,72,79)(H,84,85)(H4,62,63,65)/t32-,39-,40-,41-,42-,43-,44-,45-,46-/m0/s1
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| InChIKey |
OGNWPDVTXMDCHR-PYRLQILWSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Type-1 angiotensin II receptor | Target Info | Inhibitor | [530710] | |
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
| Pathway Interaction Database | Arf6 trafficking events | ||||
| Arf6 signaling events | |||||
| Angiopoietin receptor Tie2-mediated signaling | |||||
| PathWhiz Pathway | Angiotensin Metabolism | ||||
| Muscle/Heart Contraction | |||||
| References | |||||