Drug Information

Drug General Information
Drug ID
D0W0QF
Former ID
DNC012407
Drug Name
4-Methyl-N-(4-phenyl-thiazol-2-yl)-benzamide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [526099]
Formula
C17H14N2OS
Canonical SMILES
CC1=CC=C(C=C1)C(=O)NC2=NC(=CS2)C3=CC=CC=C3
InChI
1S/C17H14N2OS/c1-12-7-9-14(10-8-12)16(20)19-17-18-15(11-21-17)13-5-3-2-4-6-13/h2-11H,1H3,(H,18,19,20)
InChIKey
NERONVMZIDSIRT-UHFFFAOYSA-N
PubChem Compound ID
577347
Target and Pathway
Target(s) Adenosine A1 receptor Target Info Inhibitor [526099]
KEGG Pathway cGMP-PKG signaling pathway
cAMP signaling pathway
Sphingolipid signaling pathway
Neuroactive ligand-receptor interaction
Morphine addiction
NetPath Pathway TCR Signaling Pathway
RANKL Signaling Pathway
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Reactome Adenosine P1 receptors
G alpha (i) signalling events
WikiPathways Nucleotide GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 526099Bioorg Med Chem Lett. 2001 Aug 6;11(15):2017-9.Substituted 4-phenyl-2-(phenylcarboxamido)-1,3-thiazole derivatives as antagonists for the adenosine A(1) receptor.
Ref 526099Bioorg Med Chem Lett. 2001 Aug 6;11(15):2017-9.Substituted 4-phenyl-2-(phenylcarboxamido)-1,3-thiazole derivatives as antagonists for the adenosine A(1) receptor.