Drug General Information
Drug ID
D0Z0IR
Former ID
DNC009754
Drug Name
3-Phenylcyclopentanecarboxylic acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529980]
Formula
C12H14O2
Canonical SMILES
C1CC(CC1C2=CC=CC=C2)C(=O)O
InChI
1S/C12H14O2/c13-12(14)11-7-6-10(8-11)9-4-2-1-3-5-9/h1-5,10-11H,6-8H2,(H,13,14)
InChIKey
IWOLSKRVZNXDNU-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) Aldo-keto reductase family 1 member C3 Target Info Inhibitor [529980]
BioCyc Pathway Superpathway of steroid hormone biosynthesis
Allopregnanolone biosynthesis
Androgen biosynthesis
KEGG Pathway Steroid hormone biosynthesis
Arachidonic acid metabolism
Metabolic pathways
Ovarian steroidogenesis
NetPath Pathway TGF_beta_Receptor Signaling Pathway
PathWhiz Pathway Arachidonic Acid Metabolism
Reactome Retinoid metabolism and transport
WikiPathways Metapathway biotransformation
Benzo(a)pyrene metabolism
Arachidonic acid metabolism
References
Ref 529980Eur J Med Chem. 2009 Jun;44(6):2563-71. Epub 2009 Feb 5.New cyclopentane derivatives as inhibitors of steroid metabolizing enzymes AKR1C1 and AKR1C3.
Ref 529980Eur J Med Chem. 2009 Jun;44(6):2563-71. Epub 2009 Feb 5.New cyclopentane derivatives as inhibitors of steroid metabolizing enzymes AKR1C1 and AKR1C3.