Target General Information
Target ID T83793
Target Name HIV Negative factor (nef) Target Info
Gene Name nef
Species Human immunodeficiency virus type 1 (HIV-1)
Uniprot ID NEF_HV1A2
Sequence MGGKWSKRSMGGWSAIRERMRRAEPRAEPAADGVGAVSRDLEKHGAITSSNTAATNADCA
WLEAQEEEEVGFPVRPQVPLRPMTYKAALDISHFLKEKGGLEGLIWSQRRQEILDLWIYH
TQGYFPDWQNYTPGPGIRYPLTFGWCFKLVPVEPEKVEEANEGENNSLLHPMSLHGMEDA
EKEVLVWRFDSKLAFHHMARELHPEYYKDC [Human immunodeficiency virus
type 1 (HIV-1)]
Drug Resistance Mutation and Corresponding Drugs
Mutation Info Missense: D174N
Reference
Ref 1559256Inhibition of human immunodeficiency virus type 1 by triciribine involves the accessory protein nef.Antimicrob Agents Chemother.2010 Apr;54(4):1512-9.