Target General Information
Target ID T95678
Target Name Influenza Proton channel protein (M2) Target Info
Gene Name M2
Species Influenza A viruses H1N1
Uniprot ID M2_I35A3
Sequence MSLLTEVETPIRNEWGCRCNGSSDPLVIAASIIGILHLILWILDRLLFKCIYRRFKYGLK
RGPSTEGVPESMREEYRKEQQSAVDADDGHFVNIEPE [Influenza A viruses H
1N1]
Drug Resistance Mutation and Corresponding Drugs
Mutation Info Missense: S31N
Reference
Ref 556136Discovery of Potential, Non-Toxic Influenza Virus Inhibitor by Computational Techniques. Mol Inform. 2014 Aug;33(8):559-65. doi: 10.1002/minf.201400041. Epub 2014 Jul 24.
Ref 556158Design and expeditious synthesis of organosilanes as potent antivirals targeting multidrug-resistant influenza A viruses. Eur J Med Chem. 2017 Jul 28;135:70-76. doi: 10.1016/j.ejmech.2017.04.038. Epub 2017 Apr 20.
Ref 1559258Investigation of a recent rise of dual amantadine-resistance mutations in the influenza A M2 sequence.BMC Genet.2015;16 Suppl 2:S3.