Drug Information

Drug General Information
Drug ID
D06QFO
Former ID
DNC004861
Drug Name
(5-(pyridin-3-yl)furan-2-yl)methanamine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528540]
Formula
C10H10N2O
Canonical SMILES
C1=CC(=CN=C1)C2=CC=C(O2)CN
InChI
1S/C10H10N2O/c11-6-9-3-4-10(13-9)8-2-1-5-12-7-8/h1-5,7H,6,11H2
InChIKey
LENAVORGWBTPJR-UHFFFAOYSA-N
PubChem Compound ID
11332763
Target and Pathway
Target(s) Cytochrome P450 2D6 Target Info Inhibitor [528540]
KEGG Pathway Metabolism of xenobiotics by cytochrome P450
Drug metabolism - cytochrome P450
Serotonergic synapse
Reactome Xenobiotics
WikiPathways Metapathway biotransformation
Tamoxifen metabolism
Oxidation by Cytochrome P450
Vitamin D Receptor Pathway
Aripiprazole Metabolic Pathway
Fatty Acid Omega Oxidation
Codeine and Morphine Metabolism
References
Ref 528540J Med Chem. 2006 Nov 30;49(24):6987-7001.Synthetic inhibitors of cytochrome P-450 2A6: inhibitory activity, difference spectra, mechanism of inhibition, and protein cocrystallization.
Ref 528540J Med Chem. 2006 Nov 30;49(24):6987-7001.Synthetic inhibitors of cytochrome P-450 2A6: inhibitory activity, difference spectra, mechanism of inhibition, and protein cocrystallization.