Drug Information

Drug General Information
Drug ID
D00MFZ
Former ID
DNC009509
Drug Name
L-Isofagomine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529573]
Formula
C6H13NO3
Canonical SMILES
C1C(C(C(CN1)O)O)CO
InChI
1S/C6H13NO3/c8-3-4-1-7-2-5(9)6(4)10/h4-10H,1-3H2/t4-,5-,6-/m0/s1
InChIKey
QPYJXFZUIJOGNX-ZLUOBGJFSA-N
PubChem Compound ID
44578588
Target and Pathway
Target(s) Glucosylceramidase Target Info Inhibitor [529573]
KEGG Pathway Other glycan degradation
Sphingolipid metabolism
Metabolic pathways
Lysosome
PathWhiz Pathway Sphingolipid Metabolism
Reactome Glycosphingolipid metabolism
WikiPathways Sphingolipid metabolism
References
Ref 529573Bioorg Med Chem. 2008 Aug 1;16(15):7330-6. Epub 2008 Jun 18.In vitro inhibition of glycogen-degrading enzymes and glycosidases by six-membered sugar mimics and their evaluation in cell cultures.
Ref 529573Bioorg Med Chem. 2008 Aug 1;16(15):7330-6. Epub 2008 Jun 18.In vitro inhibition of glycogen-degrading enzymes and glycosidases by six-membered sugar mimics and their evaluation in cell cultures.