Drug Information

Drug General Information
Drug ID
D09FDZ
Former ID
DNC014179
Drug Name
7,8,4'-trihydroxyisoflavone
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530587]
Formula
C15H10O5
Canonical SMILES
C1=CC(=CC=C1C2=COC3=C(C2=O)C=CC(=C3O)O)O
InChI
1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-15-10(13(11)18)5-6-12(17)14(15)19/h1-7,16-17,19H
InChIKey
BMZFZTMWBCFKSS-UHFFFAOYSA-N
PubChem Compound ID
5466139
Target and Pathway
Target(s) Tyrosine oxidase Target Info Inhibitor [530587]
BioCyc Pathway (S)-reticuline biosynthesis
Eumelanin biosynthesis
L-dopachrome biosynthesis
KEGG Pathway Tyrosine metabolism
Riboflavin metabolism
Metabolic pathways
Melanogenesis
PathWhiz Pathway Riboflavin Metabolism
Tyrosine Metabolism
WikiPathways Dopamine metabolism
References
Ref 530587Bioorg Med Chem Lett. 2010 Feb 1;20(3):1162-4. Epub 2009 Dec 6.Natural ortho-dihydroxyisoflavone derivatives from aged Korean fermented soybean paste as potent tyrosinase and melanin formation inhibitors.
Ref 530587Bioorg Med Chem Lett. 2010 Feb 1;20(3):1162-4. Epub 2009 Dec 6.Natural ortho-dihydroxyisoflavone derivatives from aged Korean fermented soybean paste as potent tyrosinase and melanin formation inhibitors.