Drug Information

Drug General Information
Drug ID
D04VYZ
Former ID
DNC007219
Drug Name
2-(3''-(benzotriazole-1''-yl)ethyloxy)adenosine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528748]
Formula
C18H20N8O5
Canonical SMILES
C1=CC=C2C(=C1)N=NN2CCOC3=NC4=C(C(=N3)N)N=CN4C5C(C(C(O5)<br />CO)O)O
InChI
1S/C18H20N8O5/c19-15-12-16(25(8-20-12)17-14(29)13(28)11(7-27)31-17)22-18(21-15)30-6-5-26-10-4-2-1-3-9(10)23-24-26/h1-4,8,11,13-14,17,27-29H,5-7H2,(H2,19,21,22)/t11-,13-,14-,17-/m1/s1
InChIKey
DNLYYBHYIBDUCX-LSCFUAHRSA-N
PubChem Compound ID
16202842
Target and Pathway
Target(s) Adenosine A3 receptor Target Info Inhibitor [528748]
Reactome Adenosine P1 receptors
G alpha (i) signalling events
WikiPathways Nucleotide GPCRs
GPCRs, Class A Rhodopsin-like
GPCRs, Other
References
Ref 528748J Med Chem. 2007 Apr 19;50(8):1810-27. Epub 2007 Mar 23.Structure-activity relationships of 2,N(6),5'-substituted adenosine derivatives with potent activity at the A2B adenosine receptor.
Ref 528748J Med Chem. 2007 Apr 19;50(8):1810-27. Epub 2007 Mar 23.Structure-activity relationships of 2,N(6),5'-substituted adenosine derivatives with potent activity at the A2B adenosine receptor.