TTD | Drug: D03ALC

Drug General Information
Drug ID	D03ALC
Former ID	DNC001075
Drug Name	Oxindole 16 (compound 3)
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[535564]
Formula	C14H19F6N7O8
Canonical SMILES	C1CN2C(=NC(C3C2(C1(O)O)N=C(N3)N)COC(=O)N)N.C(=O)(C(F)(F<br />)F)O.C(=O)(C(F)(F)F)O
InChI	1S/C10H17N7O4.2C2HF3O2/c11-6-15-5-4(3-21-8(13)18)14-7(12)17-2-1-9(19,20)10(5,17)16-6;23-2(4,5)1(6)7/h4-5,19-20H,1-3H2,(H2,12,14)(H2,13,18)(H3,11,15,16);2(H,6,7)/t4-,5-,10-;;/m0../s1
InChIKey	YOPZUWVTAZLOMO-UIPPETONSA-N
CAS Number	CAS 11017-04-2
PubChem Compound ID	11692221
PubChem Substance ID	16796551, 42859139, 79213135, 134340323
Target and Pathway
Target(s)	Cell division protein kinase 8	Target Info	Inhibitor	[535564]
Target(s)	Cell division protein kinase 5	Target Info	Inhibitor	[535564]
KEGG Pathway	Axon guidance
	Alzheimer's disease
	Cocaine addiction
NetPath Pathway	EGFR1 Signaling Pathway
NetPath Pathway	TCR Signaling Pathway
PANTHER Pathway	Axon guidance mediated by semaphorins
Pathway Interaction Database	Reelin signaling pathway
	Glucocorticoid receptor regulatory network
	Lissencephaly gene (LIS1) in neuronal migration and development
	EPHA forward signaling
	Trk receptor signaling mediated by the MAPK pathway
Reactome	PPARA activates gene expression
	NOTCH1 Intracellular Domain Regulates Transcription
	SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
	Constitutive Signaling by NOTCH1 PEST Domain Mutants
	Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
	Transcriptional regulation of white adipocyte differentiationR-HSA-180024:DARPP-32 events
	CRMPs in Sema3A signaling
	Factors involved in megakaryocyte development and platelet production
WikiPathways	Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
	Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
	Transcriptional Regulation of White Adipocyte Differentiation
	Signaling by NOTCH1
	SREBP signalling
	Generic Transcription PathwayWP707:DNA Damage Response
	BDNF signaling pathway
	Alzheimers Disease
	Opioid Signalling
	Semaphorin interactions
	Factors involved in megakaryocyte development and platelet production
	Nicotine Activity on Dopaminergic Neurons
	miRNA Regulation of DNA Damage Response
References
Ref 535564	Pharmacological inhibitors of cyclin-dependent kinases. Trends Pharmacol Sci. 2002 Sep;23(9):417-25.
Ref 535564	Pharmacological inhibitors of cyclin-dependent kinases. Trends Pharmacol Sci. 2002 Sep;23(9):417-25.

Drug Information