Drug Information

Drug General Information
Drug ID
D0C8CR
Former ID
DNC011503
Drug Name
9H-beta-Carbolin-6-ylamine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [533414]
Formula
C11H9N3
Canonical SMILES
C1=CC2=C(C=C1N)C3=C(N2)C=NC=C3
InChI
1S/C11H9N3/c12-7-1-2-10-9(5-7)8-3-4-13-6-11(8)14-10/h1-6,14H,12H2
InChIKey
PPCJCNSRVOYTKC-UHFFFAOYSA-N
PubChem Compound ID
317218
Target and Pathway
Target(s) Gamma-aminobutyric acid receptor subunit alpha-1 Target Info Inhibitor [533414]
Gamma-aminobutyric acid receptor Target Info Inhibitor [533414]
KEGG Pathway Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
GABAergic synapse
Morphine addiction
Nicotine addiction
Reactome Ligand-gated ion channel transport
GABA A receptor activation
WikiPathways SIDS Susceptibility Pathways
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transport
References
Ref 533414J Med Chem. 1987 Apr;30(4):750-3.Synthesis of 6-substituted beta-carbolines that behave as benzodiazepine receptor antagonists or inverse agonists.
Ref 533414J Med Chem. 1987 Apr;30(4):750-3.Synthesis of 6-substituted beta-carbolines that behave as benzodiazepine receptor antagonists or inverse agonists.