Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0D8AN
|
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| Former ID |
DNC009077
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| Drug Name |
6-desoxonaltrexone
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [530013] | ||
| Formula |
C20H25NO3
|
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| Canonical SMILES |
C1CC2C34CCN(C(C3(C1)O)CC5=C4C(=C(C=C5)O)O2)CC6CC6
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| InChI |
1S/C20H25NO3/c22-14-6-5-13-10-15-20(23)7-1-2-16-19(20,17(13)18(14)24-16)8-9-21(15)11-12-3-4-12/h5-6,12,15-16,22-23H,1-4,7-11H2/t15-,16+,19-,20-/m1/s1
|
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| InChIKey |
XBPQMXFKKJADMC-WOUAJJJCSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Mu-type opioid receptor | Target Info | Inhibitor | [530013] | |
| Delta-type opioid receptor | Target Info | Inhibitor | [530013] | ||
| Kappa-type opioid receptor | Target Info | Inhibitor | [530013] | ||
| NetPath Pathway | TCR Signaling Pathway | ||||
| PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | |||||
| Enkephalin releaseP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||||
| Enkephalin release | |||||
| Opioid proenkephalin pathway | |||||
| Opioid proopiomelanocortin pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||||
| Opioid prodynorphin pathway | |||||
| Pathway Interaction Database | IL4-mediated signaling events | ||||
| References | |||||