Drug Information

Drug General Information
Drug ID
D00XOQ
Former ID
DNC004540
Drug Name
SB-210313
Drug Type
Small molecular drug
Indication Discovery agent Investigative [534804]
Formula
C21H23FN4O
Canonical SMILES
C1COCCN1CCCN2C=NC(=C2C3=CC=NC=C3)C4=CC=C(C=C4)F
InChI
1S/C21H23FN4O/c22-19-4-2-17(3-5-19)20-21(18-6-8-23-9-7-18)26(16-24-20)11-1-10-25-12-14-27-15-13-25/h2-9,16H,1,10-15H2
InChIKey
ANWALZPQHPAZFO-UHFFFAOYSA-N
PubChem Compound ID
9885504
Target and Pathway
Target(s) Cytochrome P450 2D6 Target Info Inhibitor [534804]
KEGG Pathway Metabolism of xenobiotics by cytochrome P450
Drug metabolism - cytochrome P450
Serotonergic synapse
Reactome Xenobiotics
WikiPathways Metapathway biotransformation
Tamoxifen metabolism
Oxidation by Cytochrome P450
Vitamin D Receptor Pathway
Aripiprazole Metabolic Pathway
Fatty Acid Omega Oxidation
Codeine and Morphine Metabolism
References
Ref 534804Bioorg Med Chem Lett. 1998 Nov 17;8(22):3111-6.Pyrimidinylimidazole inhibitors of CSBP/p38 kinase demonstrating decreased inhibition of hepatic cytochrome P450 enzymes.
Ref 534804Bioorg Med Chem Lett. 1998 Nov 17;8(22):3111-6.Pyrimidinylimidazole inhibitors of CSBP/p38 kinase demonstrating decreased inhibition of hepatic cytochrome P450 enzymes.