Drug Information

Drug General Information
Drug ID
D0B5SF
Former ID
DNC010837
Drug Name
4-(2-(3,4-Dimethylphenylamino)ethyl)-1H-imidazole
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530846]
Formula
C13H17N3
Canonical SMILES
CC1=C(C=C(C=C1)NCCC2=CN=CN2)C
InChI
1S/C13H17N3/c1-10-3-4-12(7-11(10)2)15-6-5-13-8-14-9-16-13/h3-4,7-9,15H,5-6H2,1-2H3,(H,14,16)
InChIKey
GHCPLWBMALOXTM-UHFFFAOYSA-N
PubChem Compound ID
46222044
Target and Pathway
Target(s) Histamine H3 receptor Target Info Inhibitor [530846]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Histamine receptors
G alpha (i) signalling events
WikiPathways Monoamine Transport
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 530846J Med Chem. 2010 May 13;53(9):3840-4.Role of hydrophobic substituents on the terminal nitrogen of histamine in receptor binding and agonist activity: development of an orally active histamine type 3 receptor agonist and evaluation of its antistress activity in mice.
Ref 530846J Med Chem. 2010 May 13;53(9):3840-4.Role of hydrophobic substituents on the terminal nitrogen of histamine in receptor binding and agonist activity: development of an orally active histamine type 3 receptor agonist and evaluation of its antistress activity in mice.