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Drug Information

Drug General Information
Drug ID
D0N5BA
Former ID
DNC003113
Drug Name
9-Deazahypoxanthine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551393]
Formula
C6H5N3O
PubChem Compound ID
446221
Target and Pathway
Target(s) Purine nucleoside phosphorylase Target Info Inhibitor [551393]
BioCyc Pathway Arsenate detoxification I (glutaredoxin)
Purine nucleotides degradation
Urate biosynthesis/inosine 5'-phosphate degradation
Purine deoxyribonucleosides degradation
Purine ribonucleosides degradation to ribose-1-phosphate
Guanosine nucleotides degradation
Adenosine nucleotides degradation
Superpathway of purine nucleotide salvage
Adenine and adenosine salvage III
Guanine and guanosine salvage
KEGG Pathway Purine metabolism
Pyrimidine metabolism
Nicotinate and nicotinamide metabolism
Metabolic pathways
NetPath Pathway TCR Signaling Pathway
EGFR1 Signaling Pathway
PANTHER Pathway Adenine and hypoxanthine salvage pathway
Xanthine and guanine salvage pathway
PathWhiz Pathway Purine Metabolism
Nicotinate and Nicotinamide Metabolism
Reactome Purine salvage
Purine catabolism
WikiPathways miR-targeted genes in squamous cell - TarBase
miR-targeted genes in lymphocytes - TarBase
miR-targeted genes in leukocytes - TarBase
miR-targeted genes in epithelium - TarBase
Metabolism of nucleotides
References
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
Cite DrugMAP

Fengcheng Li, Minjie Mou, ..., Jiayi Yin*, Yang Zhang*, Feng Zhu*. DrugMAP 2.0: molecular atlas and pharma-information of all drugs. Nucleic Acids Research.
DOI: 10.1093/nar/gkae791 (2024). PMID: 39271119
Learn more about DrugMAP >
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Correspondence

Prof. Feng Zhu 
College of Pharmaceutical Sciences, Zhejiang University

Dr. Yang Zhang 
School of Pharmacy, Hebei Medical University

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