Drug Information

Drug General Information
Drug ID
D04XZP
Former ID
DNC013915
Drug Name
DIHYDROKAINATE
Drug Type
Small molecular drug
Indication Discovery agent Investigative [467809]
Formula
C10H15NO4-2
InChI
InChI=1S/C10H17NO4/c1-5(2)7-4-11-9(10(14)15)6(7)3-8(12)13/h5-7,9,11H,3-4H2,1-2H3,(H,12,13)(H,14,15)/p-2/t6-,7+,9-/m0/s1
InChIKey
JQPDCKOQOOQUSC-OOZYFLPDSA-L
PubChem Compound ID
73755099
PubChem Substance ID
178101292
Target and Pathway
Target(s) Glutamate receptor, ionotropic kainate 1 Target Info Inhibitor [529559]
KEGG Pathway Neuroactive ligand-receptor interaction
Glutamatergic synapse
PANTHER Pathway Huntington disease
Ionotropic glutamate receptor pathway
Metabotropic glutamate receptor group III pathway
Metabotropic glutamate receptor group I pathway
WikiPathways Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
References
Ref 467809(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4571).
Ref 529559J Med Chem. 2008 Jul 24;51(14):4085-92. Epub 2008 Jun 25.Chemo-enzymatic synthesis of (2S,4R)-2-amino-4-(3-(2,2-diphenylethylamino)-3-oxopropyl)pentanedioic acid: a novel selective inhibitor of human excitatory amino acid transporter subtype 2.