Drug Information

Drug General Information
Drug ID
D0HQ4M
Former ID
DNC014024
Drug Name
Isopropyl dodecylfluorophosphonate
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529440]
Formula
C15H32FO2P
Canonical SMILES
CCCCCCCCCCCCP(=O)(OC(C)C)F
InChI
1S/C15H32FO2P/c1-4-5-6-7-8-9-10-11-12-13-14-19(16,17)18-15(2)3/h15H,4-14H2,1-3H3
InChIKey
SFRALHFBKRAJPW-UHFFFAOYSA-N
PubChem Compound ID
24762154
Target and Pathway
Target(s) Fatty-acid amide hydrolase Target Info Inhibitor [529440]
Cannabinoid receptor 1 Target Info Inhibitor [529440]
Acetylcholinesterase Target Info Inhibitor [529440]
BioCyc Pathway Anandamide degradation
KEGG Pathway Retrograde endocannabinoid signalinghsa04015:Rap1 signaling pathway
Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signalinghsa00564:Glycerophospholipid metabolism
Cholinergic synapse
PANTHER Pathway Anandamide degradationP05730:Endogenous cannabinoid signalingP00042:Muscarinic acetylcholine receptor 1 and 3 signaling pathway
Muscarinic acetylcholine receptor 2 and 4 signaling pathway
Nicotinic acetylcholine receptor signaling pathway
Pathway Interaction Database N-cadherin signaling eventsatf2_pathway:ATF-2 transcription factor network
PathWhiz Pathway Phospholipid Biosynthesis
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
BDNF signaling pathway
GPCR ligand binding
GPCR downstream signaling
GPCRs, OtherWP727:Monoamine Transport
Biogenic Amine Synthesis
Acetylcholine Synthesis
Integrated Pancreatic Cancer Pathway
References
Ref 529440Nat Chem Biol. 2008 Jun;4(6):373-8. Epub 2008 Apr 27.Activation of the endocannabinoid system by organophosphorus nerve agents.
Ref 529440Nat Chem Biol. 2008 Jun;4(6):373-8. Epub 2008 Apr 27.Activation of the endocannabinoid system by organophosphorus nerve agents.