Drug General Information
Drug ID
D08CGU
Former ID
DCL000496
Drug Name
Bevacizumab + Rituximab
Synonyms
Rituxan (TN)
Drug Type
Antibody
Indication Lymphoma; Non-hodgkin's lymphoma [ICD9: 200, 202, 202.8; ICD10:C81-C86, C82-C85] Phase 3 [522045]
Company
Roche
Formula
C14H18ILiN2O3
PubChem Compound ID
Target and Pathway
Target(s) B-lymphocyte antigen CD20 Target Info [551607]
Vascular endothelial growth factor Target Info Inhibitor [551607]
KEGG Pathway Hematopoietic cell lineage
References
Ref 522045ClinicalTrials.gov (NCT00486759) A Study of Bevacizumab (Avastin) in Combination With Rituximab (MabThera) and CHOP (Cyclophosphamide, Hydroxydaunorubicin [Doxorubicin], Oncovin [Vincristine], Prednisone) Chemotherapy in Patients With Diffuse Large B-cell Lymphoma. U.S. National Institutes of Health.
Ref 551607Clinical pipeline report, company report or official report of Roche (2009).