Drug Information

Drug General Information
Drug ID
D08XGI
Former ID
DNC004123
Drug Name
(1-Phenethyl-piperidin-4-yl)-phenyl-methanone
Drug Type
Small molecular drug
Indication Discovery agent Investigative [525963]
Formula
C20H23NO
Canonical SMILES
C1CN(CCC1C(=O)C2=CC=CC=C2)CCC3=CC=CC=C3
InChI
1S/C20H23NO/c22-20(18-9-5-2-6-10-18)19-12-15-21(16-13-19)14-11-17-7-3-1-4-8-17/h1-10,19H,11-16H2
InChIKey
GEFOLRNTTIQKBZ-UHFFFAOYSA-N
PubChem Compound ID
10379653
Target and Pathway
Target(s) 5-hydroxytryptamine 2A receptor Target Info Inhibitor [525963]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Serotonergic synapse
Inflammatory mediator regulation of TRP channels
PANTHER Pathway 5HT2 type receptor mediated signaling pathway
Reactome Serotonin receptors
G alpha (q) signalling events
WikiPathways Serotonin Receptor 2 and STAT3 Signaling
Serotonin Receptor 2 and ELK-SRF/GATA4 signaling
SIDS Susceptibility Pathways
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 525963J Med Chem. 2001 Feb 15;44(4):477-501.Current and novel approaches to the drug treatment of schizophrenia.
Ref 525963J Med Chem. 2001 Feb 15;44(4):477-501.Current and novel approaches to the drug treatment of schizophrenia.