Drug Information

Drug General Information
Drug ID
D09ROW
Former ID
DNC009458
Drug Name
IMPERATORIN
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528164]
Formula
C16H14O4
Canonical SMILES
CC(=CCOC1=C2C(=CC3=C1OC=C3)C=CC(=O)O2)C
InChI
1S/C16H14O4/c1-10(2)5-7-19-16-14-12(6-8-18-14)9-11-3-4-13(17)20-15(11)16/h3-6,8-9H,7H2,1-2H3
InChIKey
OLOOJGVNMBJLLR-UHFFFAOYSA-N
PubChem Compound ID
10212
Target and Pathway
Target(s) 5-hydroxytryptamine 7 receptor Target Info Inhibitor [528164]
KEGG Pathway Ras signaling pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PathWhiz Pathway Excitatory Neural Signalling Through 5-HTR 7 and Serotonin
Reactome Serotonin receptors
G alpha (s) signalling events
WikiPathways Serotonin Receptor 4/6/7 and NR3C Signaling
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 528164J Nat Prod. 2006 Apr;69(4):536-41.Serotonergic activity-guided phytochemical investigation of the roots of Angelica sinensis.
Ref 528164J Nat Prod. 2006 Apr;69(4):536-41.Serotonergic activity-guided phytochemical investigation of the roots of Angelica sinensis.