Drug Information

Drug General Information
Drug ID
D06DDA
Former ID
DNC010843
Drug Name
6-cinnamoylhernandine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530876]
Formula
C29H31NO8
Canonical SMILES
CN1C(=O)CC23C14CC(C5=C2C(=C(C=C5)OC)O)OC4(C(C(C3)OC(=O)<br />C=CC6=CC=CC=C6)OC)OC
InChI
1S/C29H31NO8/c1-30-22(31)16-27-14-21(37-23(32)13-10-17-8-6-5-7-9-17)26(35-3)29(36-4)28(27,30)15-20(38-29)18-11-12-19(34-2)25(33)24(18)27/h5-13,20-21,26,33H,14-16H2,1-4H3/b13-10+/t20-,21-,26-,27+,28-,29+/m0/s1
InChIKey
KOKWRSAOHLOSAI-HXHZFJGXSA-N
PubChem Compound ID
46888587
Target and Pathway
Target(s) Delta-type opioid receptor Target Info Inhibitor [530876]
KEGG Pathway cGMP-PKG signaling pathway
Sphingolipid signaling pathway
Neuroactive ligand-receptor interaction
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Enkephalin release
Opioid proenkephalin pathway
Opioid proopiomelanocortin pathway
Reactome Peptide ligand-binding receptors
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 530876J Nat Prod. 2010 May 28;73(5):988-91.Hasubanan alkaloids with delta-opioid binding affinity from the aerial parts of Stephania japonica.
Ref 530876J Nat Prod. 2010 May 28;73(5):988-91.Hasubanan alkaloids with delta-opioid binding affinity from the aerial parts of Stephania japonica.