Drug Information

Drug General Information
Drug ID
D0J5DN
Former ID
DNC014180
Drug Name
7,3',4'-trihydroxyisoflavone
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530587]
Formula
C15H10O5
Canonical SMILES
C1=CC(=C(C=C1C2=COC3=C(C2=O)C=CC(=C3)O)O)O
InChI
1S/C15H10O5/c16-9-2-3-10-14(6-9)20-7-11(15(10)19)8-1-4-12(17)13(18)5-8/h1-7,16-18H
InChIKey
DDKGKOOLFLYZDL-UHFFFAOYSA-N
PubChem Compound ID
5284648
Target and Pathway
Target(s) Tyrosine oxidase Target Info Inhibitor [530587]
BioCyc Pathway (S)-reticuline biosynthesis
Eumelanin biosynthesis
L-dopachrome biosynthesis
KEGG Pathway Tyrosine metabolism
Riboflavin metabolism
Metabolic pathways
Melanogenesis
PathWhiz Pathway Riboflavin Metabolism
Tyrosine Metabolism
WikiPathways Dopamine metabolism
References
Ref 530587Bioorg Med Chem Lett. 2010 Feb 1;20(3):1162-4. Epub 2009 Dec 6.Natural ortho-dihydroxyisoflavone derivatives from aged Korean fermented soybean paste as potent tyrosinase and melanin formation inhibitors.
Ref 530587Bioorg Med Chem Lett. 2010 Feb 1;20(3):1162-4. Epub 2009 Dec 6.Natural ortho-dihydroxyisoflavone derivatives from aged Korean fermented soybean paste as potent tyrosinase and melanin formation inhibitors.