Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D07QXO
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| Former ID |
DCL000836
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| Drug Name |
HMR-2934
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| Drug Type |
Small molecular drug
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| Indication | Schizophrenia [ICD9: 295; ICD10:F20] | Terminated | [536463] | ||
| Company |
Sanofi-Aventis
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| Structure |
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Download |
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| Formula |
C24H29N7O2
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| Canonical SMILES |
CC1=C(C(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCNCC4)C5CCC<br />C5)C(=O)C
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| InChI |
1S/C24H29N7O2/c1-15-19-14-27-24(28-20-8-7-18(13-26-20)30-11-9-25-10-12-30)29-22(19)31(17-5-3-4-6-17)23(33)21(15)16(2)32/h7-8,13-14,17,25H,3-6,9-12H2,1-2H3,(H,26,27,28,29)
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| InChIKey |
AHJRHEGDXFFMBM-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| PubChem Substance ID |
8035907, 11062094, 11538604, 12015755, 14808444, 17137183, 39302900, 46394060, 57361299, 78833389, 99436913, 103461613, 103905660, 103905661, 113915142, 121280258, 124360805, 124757012, 125164718, 126580155, 126671645, 126737419, 131480762, 134339015, 134339302, 134339471, 134964422, 135262045, 135686212, 135686213, 135686228, 135686229, 136367313, 136367838, 136920362, 137184856, 137275973, 141483504, 143498887, 144116345, 152240013, 152258827, 152344089, 160647678, 162202562, 164045126, 172232465, 172919351, 177748911, 178103952
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| Target and Pathway | |||||
| Target(s) | D(4) dopamine receptor | Target Info | Antagonist | [536463] | |
| 5-hydroxytryptamine receptor | Target Info | Antagonist | [536463] | ||
| D(2) dopamine receptor | Target Info | Antagonist | [536463] | ||
| PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | |||||
| Dopamine receptor mediated signaling pathway | |||||
| Nicotine pharmacodynamics pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||||
| Nicotine pharmacodynamics pathway | |||||
| References | |||||