Drug Information

Drug General Information
Drug ID
D0TZ8C
Former ID
DNC004509
Drug Name
6-(2-Imidazol-1-yl-vinyl)-1H-quinolin-2-one
Drug Type
Small molecular drug
Indication Discovery agent Investigative [526726]
Formula
C14H11N3O
Canonical SMILES
C1=CC2=C(C=CC(=O)N2)C=C1C=CN3C=CN=C3
InChI
1S/C14H11N3O/c18-14-4-2-12-9-11(1-3-13(12)16-14)5-7-17-8-6-15-10-17/h1-10H,(H,16,18)/b7-5+
InChIKey
ULTZJAJIZBBKSG-FNORWQNLSA-N
PubChem Compound ID
14373279
Target and Pathway
Target(s) CGMP-inhibited 3',5'-cyclic phosphodiesterase A Target Info Inhibitor [526726]
KEGG Pathway Purine metabolism
cGMP-PKG signaling pathway
cAMP signaling pathway
Morphine addiction
Reactome cGMP effects
G alpha (s) signalling events
WikiPathways miR-targeted genes in muscle cell - TarBase
miR-targeted genes in lymphocytes - TarBase
References
Ref 526726J Med Chem. 1992 Feb 21;35(4):620-8.3,4-Dihydroquinolin-2(1H)-ones as combined inhibitors of thromboxane A2 synthase and cAMP phosphodiesterase.
Ref 526726J Med Chem. 1992 Feb 21;35(4):620-8.3,4-Dihydroquinolin-2(1H)-ones as combined inhibitors of thromboxane A2 synthase and cAMP phosphodiesterase.