Drug General Information
Drug ID
D09BVL
Former ID
DIB002312
Drug Name
NS-1619
Drug Type
Small molecular drug
Indication Asthma [ICD10:J45] Terminated [467609], [545014]
Company
NeuroSearch A/S
Formula
C15H8F6N2O2
InChI
InChI=1S/C15H8F6N2O2/c16-14(17,18)7-1-3-10-9(5-7)22-13(25)23(10)11-6-8(15(19,20)21)2-4-12(11)24/h1-6,24H,(H,22,25)
InChIKey
YLFMCMWKHSDUCT-UHFFFAOYSA-N
CAS Number
CAS 153587-01-0
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Maxi K potassium channel Target Info Modulator
KEGG Pathway cGMP-PKG signaling pathway
Vascular smooth muscle contraction
Insulin secretion
Salivary secretion
Pancreatic secretion
Reactome cGMP effects
WikiPathways Potassium Channels
Platelet homeostasis
References
Ref 467609(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4272).
Ref 545014Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001878)