Drug Information

Drug General Information
Drug ID
D0ZG9N
Former ID
DNC012754
Drug Name
SC-53116
Drug Type
Small molecular drug
Indication Gastric motility disorder [ICD10:K22.4] Terminated [539515], [545444]
Formula
C16H22ClN3O2
InChI
InChI=1S/C16H22ClN3O2/c1-22-15-8-13(18)12(17)7-11(15)16(21)19-9-10-4-6-20-5-2-3-14(10)20/h7-8,10,14H,2-6,9,18H2,1H3,(H,19,21)/t10-,14-/m0/s1
InChIKey
GAYSOZKZPOVDSB-HZMBPMFUSA-N
PubChem Compound ID
132337
PubChem Substance ID
10243093, 14752855, 14801551, 29310511, 48407598, 57344108, 80632341, 103210742, 103919258, 104377230, 134349959, 135088034, 135651022, 135732035, 226973447
Target and Pathway
Target(s) 5-hydroxytryptamine 4 receptor Target Info Modulator
KEGG Pathway Calcium signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
5HT4 type receptor mediated signaling pathway
PathWhiz Pathway Excitatory Neural Signalling Through 5-HTR 4 and Serotonin
Reactome Serotonin receptors
G alpha (s) signalling events
WikiPathways Serotonin Receptor 4/6/7 and NR3C Signaling
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 539515(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 238).
Ref 545444Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003270)