Drug Information

Drug General Information
Drug ID
D09AOO
Former ID
DCL001141
Drug Name
ANAVEX 2-73
Indication Breast cancer [ICD9: 174, 175; ICD10:C50] Phase 2 [531153], [532266]
Alzheimer disease [ICD9: 331; ICD10:G30] Phase 1 [549727]
Company
Anavex
Target and Pathway
Target(s) Sigma(1)-type opioid receptor Target Info Agonist [549727]
WikiPathways miR-targeted genes in squamous cell - TarBase
miR-targeted genes in lymphocytes - TarBase
References
Ref 531153Anti-amnesic and neuroprotective potentials of the mixed muscarinic receptor/sigma 1 (?1) ligand ANAVEX2-73, a novel aminotetrahydrofuran derivative. J Psychopharmacol. 2011 Aug;25(8):1101-17.
Ref 532266Blockade of Tau hyperphosphorylation and Abeta?????? generation by the aminotetrahydrofuran derivative ANAVEX2-73, a mixed muscarinic and ???receptor agonist, in a nontransgenic mouse model of Alzheimer's disease. Neuropsychopharmacology. 2013 Aug;38(9):1706-23.
Ref 5497272011 Pipeline of Anavex.
Ref 5497272011 Pipeline of Anavex.