Drug General Information
Drug ID
D0F8GK
Former ID
DNCL003804
Drug Name
LY2886721
Drug Type
Small molecular drug
Indication Alzheimer disease [ICD9: 331; ICD10:G30] Phase 2 [541610], [551857]
Company
Lilly
Formula
C18H16F2N4O2S
InChI
InChI=1S/C18H16F2N4O2S/c19-11-1-4-15(22-6-11)16(25)23-12-2-3-14(20)13(5-12)18-9-26-7-10(18)8-27-17(21)24-18/h1-6,10H,7-9H2,(H2,21,24)(H,23,25)/t10-,18-/m0/s1
InChIKey
NIDRNVHMMDAAIK-YPMLDQLKSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Beta-secretase Target Info Modulator
References
Ref 541610(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6475).
Ref 551857Clinical pipeline report, company report or official report of Eli Lilly.