Drug General Information
Drug ID
D0L4WO
Former ID
DPR000186
Drug Name
SGN-19A
Drug Type
Antibody
Indication Hematologic malignancies [ICD9: 200-209; ICD10:C81-C86] Preclinical [551669]
Company
Seattle Genetics
Target and Pathway
Target(s) B-lymphocyte antigen CD19 Target Info [551669]
KEGG Pathway PI3K-Akt signaling pathway
Hematopoietic cell lineage
B cell receptor signaling pathway
Epstein-Barr virus infection
Primary immunodeficiency
NetPath Pathway IL-7 Signaling Pathway
PANTHER Pathway B cell activation
Pathway Interaction Database BCR signaling pathway
Reactome PIP3 activates AKT signaling
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Constitutive Signaling by Aberrant PI3K in Cancer
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
WikiPathways Human Complement System
Signaling by the B Cell Receptor (BCR)
PIP3 activates AKT signaling
B Cell Receptor Signaling Pathway
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
References
Ref 5516692011 Pipeline of Seattle Genetics.
Ref 5516692011 Pipeline of Seattle Genetics.