Drug Information

Drug General Information
Drug ID
D0R0EF
Former ID
DIB003042
Drug Name
AZD-7268
Synonyms
Enkephalinergic receptor modulator (oral, depression, anxiety), AstraZeneca
Drug Type
Small molecular drug
Indication Anxiety disorder [ICD9: 300, 311; ICD10:F32, F40-F42] Phase 2 [522867], [542769]
Company
AstraZeneca plc
Formula
C29H30N4O2S
InChI
InChI=1S/C29H30N4O2S/c1-32(16-17-34)29(35)24-9-7-21(8-10-24)27(26-6-2-4-23-5-3-13-30-28(23)26)22-11-14-33(15-12-22)18-25-19-36-20-31-25/h2-10,13,19-20,34H,11-12,14-18H2,1H3
InChIKey
ZJKUETLEJYCOBO-UHFFFAOYSA-N
PubChem Compound ID
24772484
PubChem Substance ID
49694488, 57107107, 136926892, 136967410, 140491719, 223366155, 224195203, 226791489, 243637136
Target and Pathway
Target(s) Opioid receptor Target Info Modulator [550881]
References
Ref 522867ClinicalTrials.gov (NCT01020799) AZD7268 Safety and Tolerability Study. U.S. National Institutes of Health.
Ref 542769(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7824).
Ref 550881EP patent application no. 2774991, Drug delivery system for use in the treatment or diagnosis of neurological disorders.