TTD | Drug: D0VF3C

Drug General Information
Drug ID	D0VF3C
Former ID	DIB005091
Drug Name	NPC-01
Synonyms	LEP pill; Low dose estrogen progestin pill (dysmenorrhea), Nobelpharma
Indication	Dysmenorrhea [ICD9: 625.3; ICD10:N94.4-N94.6]		Phase 3	[523263]
Company	Nobelpharma Co Ltd
Target and Pathway
Target(s)	Estrogen receptor	Target Info	Modulator	[523263]
Target(s)	Progesterone receptor	Target Info	Agonist	[523263]
KEGG Pathway	Estrogen signaling pathway
	Prolactin signaling pathway
	Thyroid hormone signaling pathway
	Endocrine and other factor-regulated calcium reabsorption
	Proteoglycans in cancerhsa04114:Oocyte meiosis
	Progesterone-mediated oocyte maturation
NetPath Pathway	FSH Signaling Pathway
	EGFR1 Signaling Pathway
	RANKL Signaling Pathway
Pathway Interaction Database	Regulation of nuclear SMAD2/3 signaling
	Signaling events mediated by HDAC Class II
	Plasma membrane estrogen receptor signaling
	LKB1 signaling events
	Regulation of Telomerase
	ATF-2 transcription factor network
	AP-1 transcription factor network
	FOXM1 transcription factor network
	Validated nuclear estrogen receptor alpha network
	Signaling mediated by p38-alpha and p38-beta
	FOXA1 transcription factor networkanthraxpathway:Cellular roles of Anthrax toxin
Reactome	Nuclear signaling by ERBB4
	Nuclear Receptor transcription pathwayR-HSA-1251985:Nuclear signaling by ERBB4
	Nuclear Receptor transcription pathway
WikiPathways	Estrogen signaling pathway
	Nuclear Receptors Meta-Pathway
	Estrogen Receptor Pathway
	Signaling by ERBB4
	JAK/STAT
	Integrated Pancreatic Cancer Pathway
	Leptin signaling pathway
	miR-targeted genes in muscle cell - TarBase
	Integrated Breast Cancer Pathway
	Nuclear ReceptorsWP34:Ovarian Infertility Genes
	Nuclear Receptors
References
Ref 523263	ClinicalTrials.gov (NCT01246791) Pharmacokinetics of NPC-01 After Single Oral Administration in Healthy Female Volunteers. U.S. National Institutes of Health.
Ref 523263	ClinicalTrials.gov (NCT01246791) Pharmacokinetics of NPC-01 After Single Oral Administration in Healthy Female Volunteers. U.S. National Institutes of Health.

Drug Information