Target General Information
Target ID T00140
Target Name Arachidonate 5-lipoxygenase
Synonyms 5-LO; 5-LOX; 5-lipoxygenase; ALOX5
Target Type Successful
Gene Name ALOX5
Biochemical Class Oxidoreductases acting on single donors
UniProt ID LOX5_HUMAN
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref
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Ref 546341Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007577)
Ref 546784Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010267)
Ref 526129ABT-761 (Abbott). Curr Opin Investig Drugs. 2001 Jan;2(1):68-71.
Ref 526130Anti-inflammatory activities of LDP-392, a dual PAF receptor antagonist and 5-lipoxygenase inhibitor. Pharmacol Res. 2001 Sep;44(3):213-20.
Ref 534411Pharmacological profile of the novel potent antirheumatic 4-(2',4'-difluorobiphenyl-4-yl)-2-methyl-4-oxobutanoic acid. Arzneimittelforschung. 1997 May;47(5):648-52.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.