Target General Information
Target ID T01318
Target Name Dihydroorotate dehydrogenase
Synonyms DHOD; DHODH; DHODase; DHOdehase; Dihydroorotate dehydrogenase ; Dihydroorotate oxidase; Mitochondrially bound dihydroorotate-ubiqui oxidoreductase; PFF0160c
Target Type Successful
Gene Name DHODH
Biochemical Class Oxidoreductases acting on CH-CH group of donors
UniProt ID PYRD_HUMAN
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 541907(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6825).
Ref 536772New drugs in development for the treatment of endometriosis. Expert Opin Investig Drugs. 2008 Aug;17(8):1187-202.
Ref 532210Nat Rev Drug Discov. 2013 Feb;12(2):87-90.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.