Target expression details

Target General Information
Target ID T05031
Target Name PI3-kinase beta
Synonyms PI3Kbeta; PI3kinase subunit beta; Phosphatidylinositol 4,5bisphosphate 3kinase 110 kDa catalyticsubunit beta; Phosphatidylinositol 4,5bisphosphate 3kinase catalytic subunitbeta isoform; PtdIns3kinase subunit beta; PtdIns3kinase subunit p110beta; p110beta; PIK3CB
Target Type Clinical Trial
Gene Name PIK3CB
Biochemical Class Kinase
UniProt ID PK3CB_HUMAN
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 542804(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7878).
Ref 523929ClinicalTrials.gov (NCT01610284) Phase III Study of BKM120/Placebo With Fulvestrant in Postmenopausal Patients With Hormone Receptor Positive HER2-negative Locally Advanced or Metastatic Breast Cancer Refractory to Aromatase Inhibitor. U.S. National Institutes of Health.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.